Anthelmintics



Flubenzole ®


Tablets & Suspension
flubendazole
Tablet 100 mg.
Suspension 100 mg/5 ml
Composition
Each Flubenzole® tablet or 5ml of oral suspension contains: Flubendazole100 mg.

Indications
Flubenzole® is indicated for the treatment of single and/or mixed infections caused by:
- Threadworms (pinworms) as Enterobius Vermicularis.
- Whipworms as Trichuris Trichiura.
- Large roundworms as Ascaris Lumbricoides.
- Hookworms as Anchylostoma Duodenale, Necator Americanus.


Dosage
For adults and children over 2 years:
1- Enterobiasis: One tablet or 5ml of the oral suspension as a single dose. In case of re-infection (very common), it is recommended to repeat the dose after 2 - 4 weeks.
Important Note: Entrobiasis is easily transmitted to the other partners of the family, so it is recommended to give the same dose to the whole family.
2- Ascariasis, Trichuriasis, Ancylostomiasis and mixed infections: One tablet or 5ml of the oral suspension should be given in the morning and evening for 3 subsequent days.


How Supplied
Flubenzole® Tablets: Carton box containing (AL/PVC) strip of 6 tablets.
Flubenzole® Oral Suspension: Carton box containing a glass bottle of 30 ml.


Pharmacological Action
- Flubenzole® is a synthetic derivative of benzimidazole, having a potent and broad spectrum anthelmintic activity against the nematodes, having vermicidal and ovicidal for ova of most helminthes.
- Flubenzole® acts selectively on the micro-tubular systems of nematodes and provokes degeneration of the worm’s intestinal or absorptive cells, thereby, inhibition of glucose uptake results in depletion of parasitic glycogen stores and thus in turn results in death of the worms.




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