Composition
Each tablet contains 5 mg Selegiline Hydrochloride.
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Indications
Tonus is indicated as an adjunct in the management
of Parkinson’s disease in patients treated with
levodopa/carbidopa who exhibit deterioration in the
quality of their response to this therapy.
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Dosage
The recommended regimen for the administration of
Tonus are 10 mg per day administered as divided doses of 5 mg each taken at breakfast and lunch.
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How Supplied
Boxes of 1, 2 or 3 (AL/PVC) strips, each contains 10 tablets & an inner pamphlet.
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Mechanism of action
Selegiline is an irreversible inhibitor of monoamine oxidase (MAO), an intracellular
enzyme associated with the outer membrane of mitochondria. It acts as a selective
inhibitor of MAO type B if it is administered at the recommended dose.
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