Topical Antifungals



Mico®


Oral Gel
miconazole (micronized) 0.02 gm/1 gm
Composition
Each 1 gram of Mico® Oral Gel contains 0.02 gm of miconazole.

Indications
Oral treatment and prevention of fungal infections of the oropharynx and gastrointestinal tract.

Dosage
- For oral administration.
- Dosage is based on 15 mg/kg/day (0.625 ml/kg/day).
- Adults and elderly:
1-2 spoonfuls (5-10 ml) of gel four times per day.
- Children aged 6 years and over:
One spoonful (5 ml) of gel four times per day.


How Supplied
Carton box contains a tube of 30 gm oral gel and an inner leaflet.

Properties
Miconazole possesses an antifungal activity against the common dermatophytes and yeasts as well as an antibacterial activity against certain gram-positive bacilli and cocci.
Its activity is based on the inhibition of the ergosterol biosynthesis in fungi and the change in the composition of the lipid components in the membrane, resulting in fungal cell necrosis.



   

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